How long does it take for tramadol to start working? – Drugs.com

Tramadol extended-release capsules: food does not significantly change how fast or how much tramadol is absorbed. Tramadol extended-release tablets: by taking it with a high fat meal lowers the peak plasma concentration (by about 28%), amount of absorption (by about 16%) and slows the time to peak concentrations (by approximately 3 hours).

https://www.drugs.com/medical-answers/long-tramadol-start-working-3553891/