A multicar crash has shut down all eastbound lanes of Interstate 4 approaching State Road 528, according to FL511.

The crash before mile marker 72 has all lanes blocked as of 4:13 p.m.

Images on FL511 show emergency vehicles on scene and backed-up traffic exiting from the interstate on a detour.

Traffic was backed up more than 3 miles to before the Apopka-Vineland Road (C.R. 535) exit near Downtown Disney.

A multivehicle crash shut down Interstate 4 eastbound near the State Road 528 exit on Monday, Sept. 29, 2025. (Fl511)

At least two cars with damage were seen as well as a panel truck tipped on its side in the median area, which is a construction site.

“Motorists are advised to use caution in the area and seek alternate routes,” reads an alert from FL511.

Earlier in the afternoon, the southbound exit ramp onto S.R. 528 from Florida’s Turnpike had been shut down because of an overturned semi-truck, according to the Florida Highway Patrol.

Orange County Traffic Alert:
The southbound FL Turnpike exit ramp to SR-528 is currently blocked due to an overturned semi-truck. No injuries reported. Drivers need to use caution in the area and prepare for traffic delays. #Orlando pic.twitter.com/A2auZEGxn0

— FHP Orlando (@FHPOrlando) September 29, 2025

That closure was cleared around 4 p.m.

This is a breaking news story. Check back for updates.

https://www.orlandosentinel.com/2025/09/29/i-4-eastbound-shut-down-after-crash-near-sr-528/