Ketamine reduces microglial activation and brain monocyte … – Nature

November 23, 2025

Ketamine treatment also reduced CD45highLy6GnegLy6Chigh monocyte infiltration into the brain and dampened microglial activation (CD45lowCD11bhigh).

https://www.nature.com/articles/s41380-025-03338-w

Ketamine reduces microglial activation and brain monocyte … – Nature <body> <h1> Array ( [0] => jetamine reduces microglial activation and brain monocyte … – nature [1] => metamine reduces microglial activation and brain monocyte … – nature [2] => letamine reduces microglial activation and brain monocyte … – nature [3] => oetamine reduces microglial activation and brain monocyte … – nature [4] => ietamine reduces microglial activation and brain monocyte … – nature [5] => kwtamine reduces microglial activation and brain monocyte … – nature [6] => kstamine reduces microglial activation and brain monocyte … – nature [7] => kdtamine reduces microglial activation and brain monocyte … – nature [8] => krtamine reduces microglial activation and brain monocyte … – nature [9] => k4tamine reduces microglial activation and brain monocyte … – nature [10] => k3tamine reduces microglial activation and brain monocyte … – nature [11] => keramine reduces microglial activation and brain monocyte … – nature [12] => kefamine reduces microglial activation and brain monocyte … – nature [13] => kegamine reduces microglial activation and brain monocyte … – nature [14] => keyamine reduces microglial activation and brain monocyte … – nature [15] => ke6amine reduces microglial activation and brain monocyte … – nature [16] => ke5amine reduces microglial activation and brain monocyte … – nature [17] => ketzmine reduces microglial activation and brain monocyte … – nature [18] => ketsmine reduces microglial activation and brain monocyte … – nature [19] => ketwmine reduces microglial activation and brain monocyte … – nature [20] => ketqmine reduces microglial activation and brain monocyte … – nature [21] => ketanine reduces microglial activation and brain monocyte … – nature [22] => ketakine reduces microglial activation and brain monocyte … – nature [23] => ketajine reduces microglial activation and brain monocyte … – nature [24] => ketamune reduces microglial activation and brain monocyte … – 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nature [38] => ketamin4 reduces microglial activation and brain monocyte … – nature [39] => ketamin3 reduces microglial activation and brain monocyte … – nature [40] => ketamine eeduces microglial activation and brain monocyte … – nature [41] => ketamine deduces microglial activation and brain monocyte … – nature [42] => ketamine feduces microglial activation and brain monocyte … – nature [43] => ketamine teduces microglial activation and brain monocyte … – nature [44] => ketamine 5educes microglial activation and brain monocyte … – nature [45] => ketamine 4educes microglial activation and brain monocyte … – nature [46] => ketamine rwduces microglial activation and brain monocyte … – nature [47] => ketamine rsduces microglial activation and brain monocyte … – nature [48] => ketamine rdduces microglial activation and brain monocyte … – nature [49] => ketamine rrduces microglial activation and brain monocyte … – nature [50] => ketamine r4duces microglial activation and brain monocyte … – nature [51] => ketamine r3duces microglial activation and brain monocyte … – nature [52] => ketamine resuces microglial activation and brain monocyte … – nature [53] => ketamine rexuces microglial activation and brain monocyte … – nature [54] => ketamine recuces microglial activation and brain monocyte … – nature [55] => ketamine refuces microglial activation and brain monocyte … – nature [56] => ketamine reruces microglial activation and brain monocyte … – nature [57] => ketamine reeuces microglial activation and brain monocyte … – nature [58] => ketamine redyces microglial activation and brain monocyte … – nature [59] => ketamine redhces microglial activation and brain monocyte … – nature [60] => ketamine redjces microglial activation and brain monocyte … – nature [61] => ketamine redices microglial activation and brain monocyte … – nature [62] => ketamine red8ces microglial activation and brain monocyte … – nature [63] => ketamine red7ces microglial activation and brain monocyte … – nature [64] => ketamine reduxes microglial activation and brain monocyte … – nature [65] => ketamine reduves microglial activation and brain monocyte … – nature [66] => ketamine redufes microglial activation and brain monocyte … – nature [67] => ketamine redudes microglial activation and brain monocyte … – nature [68] => ketamine reducws microglial activation and brain monocyte … – nature [69] => ketamine reducss microglial activation and brain monocyte … – nature [70] => ketamine reducds microglial activation and brain monocyte … – nature [71] => ketamine reducrs microglial activation and brain monocyte … – nature [72] => ketamine reduc4s microglial activation and brain monocyte … – nature [73] => ketamine reduc3s microglial activation and brain monocyte … – nature [74] => ketamine reducea microglial activation and brain monocyte … – nature [75] => ketamine reducez microglial activation and brain monocyte … – nature [76] => ketamine reducex microglial activation and brain monocyte … – nature [77] => ketamine reduced microglial activation and brain monocyte … – nature [78] => ketamine reducee microglial activation and brain monocyte … – nature [79] => ketamine reducew microglial activation and brain monocyte … – nature [80] => ketamine reduces nicroglial activation and brain monocyte … – nature [81] => ketamine reduces kicroglial activation and brain monocyte … – nature [82] => ketamine reduces jicroglial activation and brain monocyte … – nature [83] => ketamine reduces mucroglial activation and brain monocyte … – nature [84] => ketamine reduces mjcroglial activation and brain monocyte … – nature [85] => ketamine reduces mkcroglial activation and brain monocyte … – nature [86] => ketamine reduces mocroglial activation and brain monocyte … – nature [87] => ketamine reduces m9croglial activation and brain monocyte … – nature [88] => ketamine reduces m8croglial activation and brain monocyte … – nature [89] => ketamine reduces mixroglial activation and brain monocyte … – nature [90] => ketamine reduces mivroglial activation and brain monocyte … – nature [91] => ketamine reduces mifroglial activation and brain monocyte … – nature [92] => ketamine reduces midroglial activation and brain monocyte … – nature [93] => ketamine reduces miceoglial activation and brain monocyte … – nature [94] => ketamine reduces micdoglial activation and brain monocyte … – nature [95] => ketamine reduces micfoglial activation and brain monocyte … – nature [96] => ketamine reduces mictoglial activation and brain monocyte … – nature [97] => ketamine reduces mic5oglial activation and brain monocyte … – nature [98] => ketamine reduces mic4oglial activation and brain monocyte … – nature [99] => ketamine reduces micriglial activation and brain monocyte … – nature [100] => ketamine reduces micrkglial activation and brain monocyte … – nature [101] => ketamine reduces micrlglial activation and brain monocyte … – nature [102] => ketamine reduces micrpglial activation and brain monocyte … – nature [103] => ketamine reduces micr0glial activation and brain monocyte … – nature [104] => ketamine reduces micr9glial activation and brain monocyte … – nature [105] => ketamine reduces microflial activation and brain monocyte … – nature [106] => ketamine reduces microvlial activation and brain monocyte … – nature [107] => ketamine reduces microblial activation and brain monocyte … – nature [108] => ketamine reduces microhlial activation and brain monocyte … – nature [109] => ketamine reduces microylial activation and brain monocyte … – nature [110] => ketamine reduces microtlial activation and brain monocyte … – nature [111] => ketamine reduces microgkial activation and brain monocyte … – nature [112] => ketamine reduces microgpial activation and brain monocyte … – nature [113] => ketamine reduces microgoial activation and brain monocyte … – nature [114] => ketamine reduces microglual activation and brain monocyte … – nature [115] => ketamine reduces microgljal activation and brain monocyte … – nature [116] => ketamine reduces microglkal activation and brain monocyte … – nature [117] => ketamine reduces microgloal activation and brain monocyte … – nature [118] => ketamine reduces microgl9al activation and brain monocyte … – nature [119] => ketamine reduces microgl8al activation and brain monocyte … – nature [120] => ketamine reduces microglizl activation and brain monocyte … – nature [121] => ketamine reduces microglisl activation and brain monocyte … – nature [122] => ketamine reduces microgliwl activation and brain monocyte … – nature [123] => ketamine reduces microgliql activation and brain monocyte … – nature [124] => ketamine reduces microgliak activation and brain monocyte … – nature [125] => ketamine reduces microgliap activation and brain monocyte … – nature [126] => ketamine reduces microgliao activation and brain monocyte … – nature [127] => ketamine reduces microglial zctivation and brain monocyte … – nature [128] => ketamine reduces microglial sctivation and brain monocyte … – nature [129] => ketamine reduces microglial wctivation and brain monocyte … – nature [130] => ketamine reduces microglial qctivation and brain monocyte … – nature [131] => ketamine reduces microglial axtivation and brain monocyte … – nature [132] => ketamine reduces microglial avtivation and brain monocyte … – nature [133] => ketamine reduces microglial aftivation and brain monocyte … – nature [134] => ketamine reduces microglial adtivation and brain monocyte … – nature [135] => ketamine reduces microglial acrivation and brain monocyte … – nature [136] => ketamine reduces microglial acfivation and brain monocyte … – nature [137] => ketamine reduces microglial acgivation and brain monocyte … – nature [138] => ketamine reduces microglial acyivation and brain monocyte … – nature [139] => ketamine reduces microglial ac6ivation and brain monocyte … – nature [140] => ketamine reduces microglial ac5ivation and brain monocyte … – nature [141] => ketamine 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[154] => ketamine reduces microglial activqtion and brain monocyte … – nature [155] => ketamine reduces microglial activarion and brain monocyte … – nature [156] => ketamine reduces microglial activafion and brain monocyte … – nature [157] => ketamine reduces microglial activagion and brain monocyte … – nature [158] => ketamine reduces microglial activayion and brain monocyte … – nature [159] => ketamine reduces microglial activa6ion and brain monocyte … – nature [160] => ketamine reduces microglial activa5ion and brain monocyte … – nature [161] => ketamine reduces microglial activatuon and brain monocyte … – nature [162] => ketamine reduces microglial activatjon and brain monocyte … – nature [163] => ketamine reduces microglial activatkon and brain monocyte … – nature [164] => ketamine reduces microglial activatoon and brain monocyte … – nature [165] => ketamine reduces microglial activat9on and brain monocyte … – nature [166] => ketamine reduces microglial activat8on and brain monocyte … – nature [167] => ketamine reduces microglial activatiin and brain monocyte … – nature [168] => ketamine reduces microglial activatikn and brain monocyte … – nature [169] => ketamine reduces microglial activatiln and brain monocyte … – nature [170] => ketamine reduces microglial activatipn and brain monocyte … – nature [171] => ketamine reduces microglial activati0n and brain monocyte … – nature [172] => ketamine reduces microglial activati9n and brain monocyte … – nature [173] => ketamine reduces microglial activatiob and brain monocyte … – nature [174] => ketamine reduces microglial activatiom and brain monocyte … – nature [175] => ketamine reduces microglial activatioj and brain monocyte … – nature [176] => ketamine reduces microglial activatioh and brain monocyte … – nature [177] => ketamine reduces microglial activation znd brain monocyte … – nature [178] => ketamine reduces microglial activation snd brain monocyte … – nature [179] => ketamine reduces microglial activation wnd brain monocyte … – nature [180] => ketamine reduces microglial activation qnd brain monocyte … – nature [181] => ketamine reduces microglial activation abd brain monocyte … – nature [182] => ketamine reduces microglial activation amd brain monocyte … – nature [183] => ketamine reduces microglial activation ajd brain monocyte … – nature [184] => ketamine reduces microglial activation ahd brain monocyte … – nature [185] => ketamine reduces microglial activation ans brain monocyte … – nature [186] => ketamine reduces microglial activation anx brain monocyte … – nature [187] => ketamine reduces microglial activation anc brain monocyte … – nature [188] => ketamine reduces microglial activation anf brain monocyte … – nature [189] => ketamine reduces microglial activation anr brain monocyte … – nature [190] => ketamine reduces microglial activation ane brain monocyte … – nature [191] => ketamine reduces microglial activation and vrain monocyte … – nature [192] => ketamine 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jonocyte … – nature [218] => ketamine reduces microglial activation and brain minocyte … – nature [219] => ketamine reduces microglial activation and brain mknocyte … – nature [220] => ketamine reduces microglial activation and brain mlnocyte … – nature [221] => ketamine reduces microglial activation and brain mpnocyte … – nature [222] => ketamine reduces microglial activation and brain m0nocyte … – nature [223] => ketamine reduces microglial activation and brain m9nocyte … – nature [224] => ketamine reduces microglial activation and brain mobocyte … – nature [225] => ketamine reduces microglial activation and brain momocyte … – nature [226] => ketamine reduces microglial activation and brain mojocyte … – nature [227] => ketamine reduces microglial activation and brain mohocyte … – nature [228] => ketamine reduces microglial activation and brain monicyte … – nature [229] => ketamine reduces microglial activation and brain monkcyte … – nature [230] => ketamine reduces microglial activation and brain monlcyte … – nature [231] => ketamine reduces microglial activation and brain monpcyte … – nature [232] => ketamine reduces microglial activation and brain mon0cyte … – nature [233] => ketamine reduces microglial activation and brain mon9cyte … – nature [234] => ketamine reduces microglial activation and brain monoxyte … – nature [235] => ketamine reduces microglial activation and brain monovyte … – nature [236] => ketamine reduces microglial activation and brain monofyte … – nature [237] => ketamine reduces microglial activation and brain monodyte … – nature [238] => ketamine reduces microglial activation and brain monoctte … – nature [239] => ketamine reduces microglial activation and brain monocgte … – nature [240] => ketamine reduces microglial activation and brain monochte … – nature [241] => ketamine reduces microglial activation and brain monocute … – nature [242] => ketamine reduces microglial activation and brain monoc7te … – nature [243] => ketamine reduces microglial activation and brain monoc6te … – nature [244] => ketamine reduces microglial activation and brain monocyre … – nature [245] => ketamine reduces microglial activation and brain monocyfe … – nature [246] => ketamine reduces microglial activation and brain monocyge … – nature [247] => ketamine reduces microglial activation and brain monocyye … – nature [248] => ketamine reduces microglial activation and brain monocy6e … – nature [249] => ketamine reduces microglial activation and brain monocy5e … – nature [250] => ketamine reduces microglial activation and brain monocytw … – nature [251] => ketamine reduces microglial activation and brain monocyts … – nature [252] => ketamine reduces microglial activation and brain monocytd … – nature [253] => ketamine reduces microglial activation and brain monocytr … – nature [254] => ketamine reduces microglial activation and brain monocyt4 … – nature [255] => ketamine reduces microglial activation and brain monocyt3 … – nature [256] => ketamine reduces microglial activation and brain monocyte ᰾ – nature [257] => ketamine reduces microglial activation and brain monocyte &#u230; – nature [258] => ketamine reduces microglial activation and brain monocyte &#i230; – nature [259] => ketamine reduces microglial activation and brain monocyte ␎ – nature [260] => ketamine reduces microglial activation and brain monocyte ῂ – nature [261] => ketamine reduces microglial activation and brain monocyte &#8q30; – nature [262] => ketamine reduces microglial activation and brain monocyte &#8w30; – nature [263] => ketamine reduces microglial activation and brain monocyte ₊ – nature [264] => ketamine reduces microglial activation and brain monocyte “ – nature [265] => ketamine reduces microglial activation and brain monocyte &#82w0; – nature [266] => ketamine reduces microglial activation and brain monocyte &#82e0; – nature [267] => ketamine reduces microglial activation and brain monocyte ‰ – nature [268] => ketamine reduces microglial activation and brain monocyte   – nature [269] => ketamine reduces microglial activation and brain monocyte &#823o; – nature [270] => ketamine reduces microglial activation and brain monocyte &#823p; – nature [271] => ketamine reduces microglial activation and brain monocyte &#823-; – nature [272] => ketamine reduces microglial activation and brain monocyte … ᰫ nature [273] => ketamine reduces microglial activation and brain monocyte … &#u211; nature [274] => ketamine reduces microglial activation and brain monocyte … &#i211; nature [275] => ketamine reduces microglial activation and brain monocyte … ⏻ nature [276] => ketamine reduces microglial activation and brain monocyte … ᾯ nature [277] => ketamine reduces microglial activation and brain monocyte … &#8q11; nature [278] => ketamine reduces microglial activation and brain monocyte … &#8w11; nature [279] => ketamine reduces microglial activation and brain monocyte … ⁷ nature [280] => ketamine reduces microglial activation and brain monocyte … ” nature [281] => ketamine reduces microglial activation and brain monocyte … &#82q1; nature [282] => ketamine reduces microglial activation and brain monocyte … — nature [283] => ketamine reduces microglial activation and brain monocyte … &#821q; nature [284] => ketamine reduces microglial activation and brain monocyte … – bature [285] => ketamine reduces microglial activation and brain monocyte … – mature [286] => ketamine reduces microglial activation and brain monocyte … – jature [287] => ketamine reduces microglial activation and brain monocyte … – hature [288] => ketamine reduces microglial activation and brain monocyte … – nzture [289] => ketamine reduces microglial activation and brain monocyte … – nsture [290] => ketamine reduces microglial activation and brain monocyte … – nwture [291] => ketamine reduces microglial activation and brain monocyte … – nqture [292] => ketamine reduces microglial activation and brain monocyte … – narure [293] => ketamine reduces microglial activation and brain monocyte … – nafure [294] => ketamine reduces microglial activation and brain monocyte … – nagure [295] => ketamine reduces microglial activation and brain monocyte … – nayure [296] => ketamine reduces microglial activation and brain monocyte … – na6ure [297] => ketamine reduces microglial activation and brain monocyte … – na5ure [298] => ketamine reduces microglial activation and brain monocyte … – natyre [299] => ketamine reduces microglial activation and brain monocyte … – nathre [300] => ketamine reduces microglial activation and brain monocyte … – natjre [301] => ketamine reduces microglial activation and brain monocyte … – natire [302] => ketamine reduces microglial activation and brain monocyte … – nat8re [303] => ketamine reduces microglial activation and brain monocyte … – nat7re [304] => ketamine reduces microglial activation and brain monocyte … – natuee [305] => ketamine reduces microglial activation and brain monocyte … – natude 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