Posted in Web Signs and Symptoms of Tuberculosis | Tuberculosis (TB) | CDC January 27, 2025 Symptoms of active tuberculosis (TB) disease depend on where the TB germs are growing in the body. Common symptoms of active TB disease include cough, pain in the chest, and coughing up blood or sputum (phlegm). https://www.cdc.gov/tb/signs-symptoms/index.html