Posted in Web Tramadol – Top 8 Things You Need to Know – Drugs.com February 21, 2025 Tramadol is approved for the treatment of pain in adults that is severe enough to require an opioid analgesic and for which other treatments do not work or are not tolerated. Tramadol can put you at risk for overdose and death. https://www.drugs.com/article/tramadol-need-to-know.html